Detalhe da pesquisa
1.
Deficits in basal and evoked striatal dopamine release following alpha-synuclein preformed fibril injection: An in vivo microdialysis study.
Eur J Neurosci
; 59(7): 1585-1603, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38356120
2.
Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition.
J Neuroinflammation
; 21(1): 108, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38664840
3.
Dopaminergic Positron Emission Tomography Imaging in the Alpha-Synuclein Preformed Fibril Model Reveals Similarities to Early Parkinson's Disease.
Mov Disord
; 37(8): 1739-1748, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35524682
4.
Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits.
Neurobiol Dis
; 141: 104947, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32422283
5.
Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.
Neurobiol Dis
; 112: 106-118, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29341898
6.
Targeted gene delivery to the enteric nervous system using AAV: a comparison across serotypes and capsid mutants.
Mol Ther
; 23(3): 488-500, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25592336
7.
Developmental origins of Parkinson's disease risk: perinatal exposure to the organochlorine pesticide dieldrin leads to sex-specific DNA modifications in critical neurodevelopmental pathways in the mouse midbrain.
bioRxiv
; 2024 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38746441
8.
Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils.
NPJ Parkinsons Dis
; 10(1): 7, 2024 Jan 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172128
9.
Microglial depletion does not impact alpha-synuclein aggregation or nigrostriatal degeneration in the rat preformed fibril model.
Res Sq
; 2023 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37205534
10.
Developmental exposure to the Parkinson's disease-associated organochlorine pesticide dieldrin alters dopamine neurotransmission in α-synuclein pre-formed fibril (PFF)-injected mice.
Toxicol Sci
; 196(1): 99-111, 2023 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607008
11.
Parkinson's disease-associated, sex-specific changes in DNA methylation at PARK7 (DJ-1), SLC17A6 (VGLUT2), PTPRN2 (IA-2ß), and NR4A2 (NURR1) in cortical neurons.
NPJ Parkinsons Dis
; 8(1): 120, 2022 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36151217
12.
Large-Scale SARS-CoV-2 Testing Utilizing Saliva and Transposition Sample Pooling.
J Vis Exp
; (184)2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35815999
13.
Epigenetic inactivation of the autophagy-lysosomal system in appendix in Parkinson's disease.
Nat Commun
; 12(1): 5134, 2021 08 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34446734
14.
Multimodal Production of Adeno-Associated Virus.
Methods Mol Biol
; 1937: 101-124, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30706392
15.
Basic Concepts in Viral Vector-Mediated Gene Therapy.
Methods Mol Biol
; 1937: 3-26, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30706387
16.
Recombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain.
Neurobiol Aging
; 36(2): 1110-20, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25457558
17.
Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system.
PLoS One
; 8(11): e81426, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24312298